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タイトル: 下肢筋群にみられる部位依存的な筋量の加齢変化 : 生活動作遂行能力との関連性から(要旨)
著者: 小川, まどか
著者(別言語): オガワ, マドカ
キーワード: 加齢
サルコペニア
筋量
生活動作
aging
sarcopenia
muscle mass
activities of daily living
発行日: 2012年3月22日
抄録: The purpose of this study was to characterize sarcopenia in the lower-limb muscles and to learn its relations to the ability to perform activities of daily living, and also to the status of daily physical activities. Experiment 1 compared the volume of each thigh muscle between young and old men with MRI measurements. Quadriceps muscle volume was lower by ~20% (P<.05) in the old than in the young men, while the volumes of hamstrings and adductor muscles were similar in both groups. The results suggest that the age-related decrease in thigh muscle volume is muscle specific, i.e., the greater decrease in the quadriceps muscle. Experiment 2 examined the correlation between the muscle thickness (MTH) measured with B-mode ultrasound and the cross-sectional area (CSA) and the volume measured with MRI for the quadriceps, hamstring, and adductor muscles. A strong correlation was observed between MTH and CSA/volume, indicating that ultrasound measurements are useful in the rapid evaluation of thigh muscle size. Experiment 3 investigated the relationship between age-related, quadriceps specific loss of thigh muscle and functional ability and gait performance. There were significant correlations (P<.05) between the MTH of anterior thigh and the performances in maximal walking speed, zig-zag walk, sit-to-stand test, while no significant correlations were found between the MTH of posterior thigh and these performance measures. The age-related loss of quadriceps muscle was lower in magnitude in the subjects with comparatively high activities of daily living. Experiment 4 investigated the relationship between age-related, quadriceps-specific loss of thigh muscle and accelerometer-determined daily physical activity. There were significant correlations (P<.05) between the MTH of anterior thigh and moderate (3.6-5.2 METs) and vigorous (6.1-8.3METs) intensity activities. However, no significant correlations were demonstrated between the MTH of posterior thigh and activities with all intensities categorized (low, moderate and vigorous). These results suggest that the age-related, quadriceps-specific loss of thigh muscle is associated with the amount of moderate and vigorous physical activity. In conclusion, the greater loss in the quadriceps muscle was characterized in sarcopenia and was related to the lower ability to perform activities of daily living. Its prevention needs activities with, at least, moderate intensity.
内容記述: 報告番号: ; 学位授与年月日: 2012-03-22 ; 学位の種別: 修士 ; 学位の種類: 修士(科学) ; 学位記番号: 修創域第4395号 ; 研究科・専攻: 新領域創成科学研究科環境学研究系人間環境学専攻
URI: http://hdl.handle.net/2261/52330
出現カテゴリ:025 修士論文
1223525 修士論文(環境学研究系人間環境学専攻)

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