Allosamidin is a chitinase inhibitor produced by Streptomyces. Allosamidin-producing Streptomyces is frequently found in soil. Allosamidin is a hydrophilic compound, but is found only in mycelia of its producer, and exogenous allosamidin is adsorbed on mycelia of its producing strain. We found that exogenous addition of allosamidin to a culture medium with colloidal chitin as a sole carbon source can strongly accelerate the chitinase production by an allosamidin-producing Streptomyces at low concentrations such as 1 μM. On the other hand, allosamidin depressed the chitinase activity in the culture of Streptomyces lividans, an allosamidin-nonproducing microbe. These results suggest that allosamidin has a physiological role in its producer as an inducer of chitinase production, which may be useful for chitin utilization by the producer in chitin-rich environment such as in soil.
雑誌名
Proceedings of the Japan Academy. Series B, Physical and biological sciences
巻
77
号
5
ページ
79 - 82
発行年
2001
ISSN
03862208
書誌レコードID
AA00785485
フォーマット
application/pdf
日本十進分類法
405
出版者
Japan Academy
出版者別名
日本学士院
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Allosamidin, a chitinase inhibitor produced by Streptomyces, acts as an inducer of chitinase production in its producing strain
JAcad77_79.pdf
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