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アイテム
Postoperative kidney function in Japanese living kidney donors
https://doi.org/10.15083/00002454
https://doi.org/10.15083/0000245434f79d2f-d8e1-454c-b7fb-f08e2ac0cc08
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h21_kido.pdf (417.2 kB)
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h21_kido_a.pdf (94.7 kB)
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| Item type | 学位論文 / Thesis or Dissertation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2012-03-01 | |||||
| タイトル | ||||||
| タイトル | Postoperative kidney function in Japanese living kidney donors | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源 | http://purl.org/coar/resource_type/c_46ec | |||||
| タイプ | thesis | |||||
| ID登録 | ||||||
| ID登録 | 10.15083/00002454 | |||||
| ID登録タイプ | JaLC | |||||
| その他のタイトル | ||||||
| その他のタイトル | 日本人生体腎移植ドナーの腎提供後腎機能 | |||||
| 著者 |
木戸, 亮
× 木戸, 亮 |
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| 著者所属 | ||||||
| 著者所属 | 大学院医学系研究科 内科学専攻 | |||||
| Abstract | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Few investigations about safety of post-donation living kidney donors have been conducted,especially in Japanese. I reviewed medical records of 1519 living kidney donors who donated inTokyo women’s medical university hospital. Using all the data or partially, I investigated theirpost-donation trends in glomerular filtration rate (GFR) and risk for kidney disease such aspersistent proteinuria or progressive renal dysfunction, and end-stage renal disease (ESRD). Most(> 90%) donors developed GFR corresponding to chronic kidney disease (CKD) stage3, however,showed stabilized trends in GFR until 3 years after donation, distinct from those of CKD patients inthe general population. Meanwhile, donors who developed ESRD had maintained GFR for longperiod, but which started to decline after having comorbidities known as progression factors ofCKD. They had higher incidence of protenuria, acute cardiovascular events, severe infection, andhospitalization due to accelerating factors of CKD than those not developing ESRD. Furthermore,donors having persistent glomerular hematuria both pre- and post-donation had significantly higherrisk for kidney disease after donation. Kidney donors might be inappropriate for labeling as CKD,however, they should be carefully evaluated and followed for long period with attention on CKDrisk factors, especially those with glomerular hematuria. | |||||
| 書誌情報 | 発行日 2010-03-24 | |||||
| 日本十進分類法 | ||||||
| 主題Scheme | NDC | |||||
| 主題 | 490 | |||||
| 学位名 | ||||||
| 学位名 | 博士(医学) | |||||
| 学位 | ||||||
| 値 | doctoral | |||||
| 学位分野 | ||||||
| Medical Science (医学) | ||||||
| 学位授与機関 | ||||||
| 学位授与機関名 | University of Tokyo (東京大学) | |||||
| 研究科・専攻 | ||||||
| Department of Internal Medicine, Graduate School of Medicine (医学系研究科内科学専攻) | ||||||
| 学位授与年月日 | ||||||
| 学位授与年月日 | 2010-03-24 | |||||
| 学位授与番号 | ||||||
| 学位授与番号 | 甲第25979号 | |||||
| 学位記番号 | ||||||
| 博医第3458号 | ||||||
