WEKO3
アイテム
{"_buckets": {"deposit": "c1af8467-5111-458f-a3fa-87949974e16d"}, "_deposit": {"id": "3863", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "3863"}, "status": "published"}, "_oai": {"id": "oai:repository.dl.itc.u-tokyo.ac.jp:00003863", "sets": ["234", "256"]}, "item_7_biblio_info_7": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2011-03-24", "bibliographicIssueDateType": "Issued"}, "bibliographic_titles": [{}]}]}, "item_7_date_granted_25": {"attribute_name": "学位授与年月日", "attribute_value_mlt": [{"subitem_dategranted": "2011-03-24"}]}, "item_7_degree_name_20": {"attribute_name": "学位名", "attribute_value_mlt": [{"subitem_degreename": "修士(科学)"}]}, "item_7_description_5": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Transplantation of stem cell-derived neurons into the damaged neuronal tissue is one of the promising methods for the recovery of neuronal functions. However, little is known about the signal transmission between transplanted stem cell-derived neuronal networks and the host brain tissue during recovery. In this study, we developed microelectrode-array (MEA) substrates with multiple micro-chambers for cell cultures. Each micro-chamber consisted of 4 cell-plating spots with interconnecting conduits fabricated by polydimethylsiloxane (PDMS) lithography. The conduits had the tunneling structures, the height of which was approximately 6 μm, through which only neurites could grow into adjacent cell-plating spots. We cultured mouse cortical and stem cell-derived neurons in the subset of cell-plating spots. Here, we discussed this co-culture device utility for monitoring of transplantation processes in vitro.", "subitem_description_type": "Abstract"}]}, "item_7_full_name_3": {"attribute_name": "著者別名", "attribute_value_mlt": [{"nameIdentifiers": [{"nameIdentifier": "9002", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "イトウ, ヒロキ"}]}]}, "item_7_select_21": {"attribute_name": "学位", "attribute_value_mlt": [{"subitem_select_item": "master"}]}, "item_7_subject_13": {"attribute_name": "日本十進分類法", "attribute_value_mlt": [{"subitem_subject": "491", "subitem_subject_scheme": "NDC"}]}, "item_7_text_24": {"attribute_name": "研究科・専攻", "attribute_value_mlt": [{"subitem_text_value": "新領域創成科学研究科環境学研究系人間環境学専攻"}]}, "item_7_text_27": {"attribute_name": "学位記番号", "attribute_value_mlt": [{"subitem_text_value": "修創域第3959号"}]}, "item_7_text_36": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"subitem_text_value": "Thesis"}]}, "item_7_text_4": {"attribute_name": "著者所属", "attribute_value_mlt": [{"subitem_text_value": "東京大学大学院新領域創成科学研究科環境学研究系人間環境学専攻"}, {"subitem_text_value": "Department of Human and Engineered Environmental Studies, Graduate School of Frontier Sciences, The University of Tokyo"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "伊藤, 宏樹"}], "nameIdentifiers": [{"nameIdentifier": "9001", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2017-05-31"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "K-02836-a.pdf", "filesize": [{"value": "562.6 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 562600.0, "url": {"label": "要旨(summary)", "url": "https://repository.dl.itc.u-tokyo.ac.jp/record/3863/files/K-02836-a.pdf"}, "version_id": "b7322e72-30f0-4147-8fc5-d03063f5ec3c"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "microelectrode array", "subitem_subject_scheme": "Other"}, {"subitem_subject": "neuronal network", "subitem_subject_scheme": "Other"}, {"subitem_subject": "patterned culture", "subitem_subject_scheme": "Other"}, {"subitem_subject": "microstructure", "subitem_subject_scheme": "Other"}, {"subitem_subject": "tissue engineering", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "jpn"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "thesis", "resourceuri": "http://purl.org/coar/resource_type/c_46ec"}]}, "item_title": "分化誘導細胞 : 生体由来細胞系共培養デバイスの開発(要旨)", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "分化誘導細胞 : 生体由来細胞系共培養デバイスの開発(要旨)"}]}, "item_type_id": "7", "owner": "1", "path": ["234", "256"], "permalink_uri": "http://hdl.handle.net/2261/48981", "pubdate": {"attribute_name": "公開日", "attribute_value": "2012-10-12"}, "publish_date": "2012-10-12", "publish_status": "0", "recid": "3863", "relation": {}, "relation_version_is_last": true, "title": ["分化誘導細胞 : 生体由来細胞系共培養デバイスの開発(要旨)"], "weko_shared_id": null}
分化誘導細胞 : 生体由来細胞系共培養デバイスの開発(要旨)
http://hdl.handle.net/2261/48981
http://hdl.handle.net/2261/48981de889ecd-20aa-441c-8090-b766b9549cf4
名前 / ファイル | ライセンス | アクション |
---|---|---|
要旨(summary) (562.6 kB)
|
|
Item type | 学位論文 / Thesis or Dissertation(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2012-10-12 | |||||
タイトル | ||||||
タイトル | 分化誘導細胞 : 生体由来細胞系共培養デバイスの開発(要旨) | |||||
言語 | ||||||
言語 | jpn | |||||
キーワード | ||||||
主題 | microelectrode array | |||||
主題Scheme | Other | |||||
キーワード | ||||||
主題 | neuronal network | |||||
主題Scheme | Other | |||||
キーワード | ||||||
主題 | patterned culture | |||||
主題Scheme | Other | |||||
キーワード | ||||||
主題 | microstructure | |||||
主題Scheme | Other | |||||
キーワード | ||||||
主題 | tissue engineering | |||||
主題Scheme | Other | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_46ec | |||||
タイプ | thesis | |||||
著者 |
伊藤, 宏樹
× 伊藤, 宏樹 |
|||||
著者別名 | ||||||
識別子 | 9002 | |||||
識別子Scheme | WEKO | |||||
姓名 | イトウ, ヒロキ | |||||
著者所属 | ||||||
著者所属 | 東京大学大学院新領域創成科学研究科環境学研究系人間環境学専攻 | |||||
著者所属 | ||||||
著者所属 | Department of Human and Engineered Environmental Studies, Graduate School of Frontier Sciences, The University of Tokyo | |||||
Abstract | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Transplantation of stem cell-derived neurons into the damaged neuronal tissue is one of the promising methods for the recovery of neuronal functions. However, little is known about the signal transmission between transplanted stem cell-derived neuronal networks and the host brain tissue during recovery. In this study, we developed microelectrode-array (MEA) substrates with multiple micro-chambers for cell cultures. Each micro-chamber consisted of 4 cell-plating spots with interconnecting conduits fabricated by polydimethylsiloxane (PDMS) lithography. The conduits had the tunneling structures, the height of which was approximately 6 μm, through which only neurites could grow into adjacent cell-plating spots. We cultured mouse cortical and stem cell-derived neurons in the subset of cell-plating spots. Here, we discussed this co-culture device utility for monitoring of transplantation processes in vitro. | |||||
書誌情報 | 発行日 2011-03-24 | |||||
日本十進分類法 | ||||||
主題 | 491 | |||||
主題Scheme | NDC | |||||
学位名 | ||||||
学位名 | 修士(科学) | |||||
学位 | ||||||
値 | master | |||||
研究科・専攻 | ||||||
新領域創成科学研究科環境学研究系人間環境学専攻 | ||||||
学位授与年月日 | ||||||
学位授与年月日 | 2011-03-24 | |||||
学位記番号 | ||||||
修創域第3959号 |