{"created":"2021-03-01T06:22:10.353760+00:00","id":5475,"links":{},"metadata":{"_buckets":{"deposit":"0dc18c94-a9c4-4cf4-976e-a88bf0c32e30"},"_deposit":{"id":"5475","owners":[],"pid":{"revision_id":0,"type":"depid","value":"5475"},"status":"published"},"_oai":{"id":"oai:repository.dl.itc.u-tokyo.ac.jp:00005475","sets":["125:355:356","9:233:280"]},"item_7_alternative_title_1":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Results of multicenter, randomized controlled trial of prevention of post-ERCP pancreatitis with Risperidone"}]},"item_7_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2013-03-25","bibliographicIssueDateType":"Issued"},"bibliographic_titles":[{}]}]},"item_7_date_granted_25":{"attribute_name":"学位授与年月日","attribute_value_mlt":[{"subitem_dategranted":"2013-03-25"}]},"item_7_degree_grantor_23":{"attribute_name":"学位授与機関","attribute_value_mlt":[{"subitem_degreegrantor":[{"subitem_degreegrantor_name":"University of Tokyo (東京大学)"}]}]},"item_7_degree_name_20":{"attribute_name":"学位名","attribute_value_mlt":[{"subitem_degreename":"博士(医学)"}]},"item_7_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"内視鏡的逆行性膵胆管造影（ERCP）の偶発症の中で、急性膵炎は最も頻度が高く、また、重症化する場合もある。ERCP後膵炎の予防のため、種々の薬剤の予防的投与に関する試験が国内外で施行されたが、未だに確立したものはない。セロトニンは、腸管の化学的、機械的刺激により膵外分泌を促進させる。また、血小板凝集、血管収縮、IL-6、TNF産生誘導作用により、膵炎重症化に寄与している可能性もある。今回セロトニン受容体拮抗薬であるリスペリドンのERCP後膵炎予防効果を多施設共同無作為化二重盲検群間比較試験にて検討した。リスペリドンは、ERCP3時間後のAmylase上昇は抑制したものの、膵炎予防効果は認めなかった。","subitem_description_type":"Abstract"}]},"item_7_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.15083/00005466","subitem_identifier_reg_type":"JaLC"}]},"item_7_select_21":{"attribute_name":"学位","attribute_value_mlt":[{"subitem_select_item":"doctoral"}]},"item_7_text_22":{"attribute_name":"学位分野","attribute_value_mlt":[{"subitem_text_value":"Medical Science(医学)"}]},"item_7_text_24":{"attribute_name":"研究科・専攻","attribute_value_mlt":[{"subitem_text_value":"Department of Internal Medicine, Graduate School of Medicine(医学系研究科内科学専攻)"}]},"item_7_text_4":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"東京大学医学系研究科内科学専攻"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"内野, 里枝"}],"nameIdentifiers":[{"nameIdentifier":"11418","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-06-01"}],"displaytype":"detail","filename":"H24_4063_uchino.pdf","filesize":[{"value":"896.3 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"H24_4063_uchino.pdf","url":"https://repository.dl.itc.u-tokyo.ac.jp/record/5475/files/H24_4063_uchino.pdf"},"version_id":"2b6df287-d466-4f08-90c4-349881029e89"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"thesis","resourceuri":"http://purl.org/coar/resource_type/c_46ec"}]},"item_title":"内視鏡的逆行性膵胆管造影（ERCP）後膵炎発症予防におけるリスペリドンの有効性に関する多施設共同無作為化比較試験による検討","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"内視鏡的逆行性膵胆管造影（ERCP）後膵炎発症予防におけるリスペリドンの有効性に関する多施設共同無作為化比較試験による検討"}]},"item_type_id":"7","owner":"1","path":["280","356"],"pubdate":{"attribute_name":"公開日","attribute_value":"2014-01-14"},"publish_date":"2014-01-14","publish_status":"0","recid":"5475","relation_version_is_last":true,"title":["内視鏡的逆行性膵胆管造影（ERCP）後膵炎発症予防におけるリスペリドンの有効性に関する多施設共同無作為化比較試験による検討"],"weko_creator_id":"1","weko_shared_id":null},"updated":"2022-12-19T03:47:03.347251+00:00"}