{"created":"2021-03-01T06:22:17.124929+00:00","id":5585,"links":{},"metadata":{"_buckets":{"deposit":"52276d64-712e-4b8d-a56a-468905887e36"},"_deposit":{"id":"5585","owners":[],"pid":{"revision_id":0,"type":"depid","value":"5585"},"status":"published"},"_oai":{"id":"oai:repository.dl.itc.u-tokyo.ac.jp:00005585","sets":["125:423:424","9:233:280"]},"item_7_alternative_title_1":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Quantitative electroencephalogram potentiation as cumulative effects of left prefrontal repetitive transcranial magnetic stimulation in major depression"}]},"item_7_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2012-03-22","bibliographicIssueDateType":"Issued"},"bibliographic_titles":[{}]}]},"item_7_date_granted_25":{"attribute_name":"学位授与年月日","attribute_value_mlt":[{"subitem_dategranted":"2012-03-22"}]},"item_7_degree_grantor_23":{"attribute_name":"学位授与機関","attribute_value_mlt":[{"subitem_degreegrantor":[{"subitem_degreegrantor_name":"University of Tokyo (東京大学)"}]}]},"item_7_degree_name_20":{"attribute_name":"学位名","attribute_value_mlt":[{"subitem_degreename":"博士(医学)"}]},"item_7_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"本研究では薬物治療抵抗性の大うつ病性障害を対象に反復性高頻度経頭蓋磁気刺激法(rTMS)による定量脳波(qEEG)への影響及び臨床効果について調べた。うつ病患者25名に対して、計10回のrTMSセッションを左背外側前頭前野に施行した。その前後で安静覚醒閉眼脳波を計測し、パワースペクトラム解析を行った。rTMSによる臨床効果はハミルトンうつ病評価尺度とウィスコンシンカードソーティングテストで評価した。前頭前野領域を対象としたqEEGパワー変化の分散分析では、rTMS治療後にシータパワーの有意な増加を認めた。F3, Fz, F4を対象とした相関分析では、F3/F4のシータパワーの増高と認知機能改善との間に有意な臨床相関を認めた。本研究結果からは、うつ病に対するrTMS治療により、長期増強様変化を反映したqEEG変化が引き起こされている可能性が示唆された。","subitem_description_type":"Abstract"}]},"item_7_dissertation_number_26":{"attribute_name":"学位授与番号","attribute_value_mlt":[{"subitem_dissertationnumber":"甲第28179号"}]},"item_7_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"11628","nameIdentifierScheme":"WEKO"}],"names":[{"name":"のだ, よしひろ"}]}]},"item_7_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.15083/00005576","subitem_identifier_reg_type":"JaLC"}]},"item_7_select_21":{"attribute_name":"学位","attribute_value_mlt":[{"subitem_select_item":"doctoral"}]},"item_7_subject_13":{"attribute_name":"日本十進分類法","attribute_value_mlt":[{"subitem_subject":"490","subitem_subject_scheme":"NDC"}]},"item_7_text_22":{"attribute_name":"学位分野","attribute_value_mlt":[{"subitem_text_value":"Medical Science(医学)"}]},"item_7_text_24":{"attribute_name":"研究科・専攻","attribute_value_mlt":[{"subitem_text_value":"Department of Neurosciences, Graduate School of Medicine (医学系研究科脳神経医学専攻)"}]},"item_7_text_27":{"attribute_name":"学位記番号","attribute_value_mlt":[{"subitem_text_value":"博医第3838号"}]},"item_7_text_4":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"東京大学大学院医学系研究科脳神経医学専攻"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"野田, 賀大"}],"nameIdentifiers":[{"nameIdentifier":"11627","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-06-01"}],"displaytype":"detail","filename":"h23_noda.pdf","filesize":[{"value":"907.3 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"h23_noda.pdf","url":"https://repository.dl.itc.u-tokyo.ac.jp/record/5585/files/h23_noda.pdf"},"version_id":"f641e60a-d5b9-4b0c-8d0a-10af3b95d719"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"thesis","resourceuri":"http://purl.org/coar/resource_type/c_46ec"}]},"item_title":"大うつ病性障害の左背外側前頭前野への反復性高頻度経頭蓋磁気刺激法による定量脳波増強効果についての研究","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"大うつ病性障害の左背外側前頭前野への反復性高頻度経頭蓋磁気刺激法による定量脳波増強効果についての研究"}]},"item_type_id":"7","owner":"1","path":["280","424"],"pubdate":{"attribute_name":"公開日","attribute_value":"2014-02-24"},"publish_date":"2014-02-24","publish_status":"0","recid":"5585","relation_version_is_last":true,"title":["大うつ病性障害の左背外側前頭前野への反復性高頻度経頭蓋磁気刺激法による定量脳波増強効果についての研究"],"weko_creator_id":"1","weko_shared_id":null},"updated":"2022-12-19T03:47:10.756833+00:00"}