{"created":"2021-03-01T06:17:13.041026+00:00","id":673,"links":{},"metadata":{"_buckets":{"deposit":"1bd51101-a83e-43e7-b5e0-1a3a7e16c4e2"},"_deposit":{"id":"673","owners":[],"pid":{"revision_id":0,"type":"depid","value":"673"},"status":"published"},"_oai":{"id":"oai:repository.dl.itc.u-tokyo.ac.jp:00000673","sets":["75:159:160","9:10:11"]},"item_2_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2014-06-09","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"557","bibliographicPageStart":"555","bibliographicVolumeNumber":"10","bibliographic_titles":[{"bibliographic_title":"Nature chemical biology"}]}]},"item_2_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"The Watson-Crick base pairs between the 3'-terminal end of tRNAs and ribosomal RNA in the peptidyl transferase center are universally conserved. Here, we report that the introduction of compensatory mutations to Escherichia coli RNAs in this site leads to an orthogonal system independent of the wild-type counterpart, as demonstrated via the production of two peptide sequences from a single mRNA. This work thus identifies a new way to reprogram the genetic code.","subitem_description_type":"Abstract"}]},"item_2_description_6":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"UTokyo Research掲載「１つの遺伝子から２種類のペプチドが同時に翻訳合成できる？！」 URI: http://www.u-tokyo.ac.jp/ja/utokyo-research/research-news/simultaneous-translation-of-two-distinct-peptides-from-single-mrna-template/","subitem_description_type":"Other"},{"subitem_description":"UTokyo Research \"Simultaneous translation of two distinct peptides from single mRNA template\" URI: http://www.u-tokyo.ac.jp/en/utokyo-research/research-news/simultaneous-translation-of-two-distinct-peptides-from-single-mrna-template/","subitem_description_type":"Other"}]},"item_2_publisher_20":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Nature Publishing Group"}]},"item_2_relation_11":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"info:doi/10.1038/nchembio.1549","subitem_relation_type_select":"DOI"}}]},"item_2_relation_25":{"attribute_name":"関係URI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"http://www.u-tokyo.ac.jp/ja/utokyo-research/research-news/simultaneous-translation-of-two-distinct-peptides-from-single-mrna-template/","subitem_relation_type_select":"URI"}},{"subitem_relation_type_id":{"subitem_relation_type_id_text":"http://www.u-tokyo.ac.jp/en/utokyo-research/research-news/simultaneous-translation-of-two-distinct-peptides-from-single-mrna-template/","subitem_relation_type_select":"URI"}},{"subitem_relation_type_id":{"subitem_relation_type_id_text":"http://www.nature.com/nchembio/journal/v10/n7/abs/nchembio.1549.html","subitem_relation_type_select":"URI"}}]},"item_2_rights_12":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"Copyright (C) 2014, Rights Managed by Nature Publishing Group"}]},"item_2_select_14":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"author"}]},"item_2_source_id_10":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA11994319","subitem_source_identifier_type":"NCID"}]},"item_2_source_id_8":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1552-4450","subitem_source_identifier_type":"ISSN"},{"subitem_source_identifier":"1552-4469","subitem_source_identifier_type":"ISSN"}]},"item_2_text_4":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"Department of Chemistry, Graduate School of Science, University of Tokyo"},{"subitem_text_value":"Japan Science and Technology Agency, Core Research for Evolutional Science and Technology, University of Tokyo"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Terasaka, Naohiro"}],"nameIdentifiers":[{"nameIdentifier":"2397","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Hayashi, Gosuke"}],"nameIdentifiers":[{"nameIdentifier":"2398","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Katoh, Takayuki"}],"nameIdentifiers":[{"nameIdentifier":"2399","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Suga, Hiroaki"}],"nameIdentifiers":[{"nameIdentifier":"2400","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-05-30"}],"displaytype":"detail","filename":"nchembio.1549_author_version.pdf","filesize":[{"value":"879.7 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"nchembio.1549_author_version.pdf","url":"https://repository.dl.itc.u-tokyo.ac.jp/record/673/files/nchembio.1549_author_version.pdf"},"version_id":"d9d09342-6124-449a-a144-0e018f2997ce"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"An orthogonal ribosome-tRNAs pair via engineering of the peptidyl transferase center","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"An orthogonal ribosome-tRNAs pair via engineering of the peptidyl transferase center"}]},"item_type_id":"2","owner":"1","path":["11","160"],"pubdate":{"attribute_name":"公開日","attribute_value":"2015-02-26"},"publish_date":"2015-02-26","publish_status":"0","recid":"673","relation_version_is_last":true,"title":["An orthogonal ribosome-tRNAs pair via engineering of the peptidyl transferase center"],"weko_creator_id":"1","weko_shared_id":2},"updated":"2022-12-19T03:41:39.563862+00:00"}