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Searching slgnal transduction pathways in protein-protein interaction networks
http://hdl.handle.net/2261/2273
http://hdl.handle.net/2261/22732229ec62-059c-49cd-b58e-514931c815ea
名前 / ファイル | ライセンス | アクション |
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本文(fulltext) (11.2 MB)
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Item type | 学位論文 / Thesis or Dissertation(1) | |||||
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公開日 | 2011-08-08 | |||||
タイトル | ||||||
タイトル | Searching slgnal transduction pathways in protein-protein interaction networks | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題 | slgnal transduction pathways | |||||
主題Scheme | Other | |||||
キーワード | ||||||
主題 | protein-protein interaction networks | |||||
主題Scheme | Other | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_46ec | |||||
タイプ | thesis | |||||
その他のタイトル | ||||||
その他のタイトル | タンパク質間相互作用ネットワークからシグナル伝達パスウェイを検出する手法の開発 | |||||
著者 |
岡, 弘之
× 岡, 弘之 |
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著者別名 | ||||||
識別子 | 4108 | |||||
識別子Scheme | WEKO | |||||
姓名 | Oka, Hiroyuki | |||||
Abstract | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | We developed a new method to searchfunctionally similar protein interaction networks witha glVen query Slgnal transduction pathway from protein interaction networks.This method consists of two main parts: 1)a backtracking search algorithm to find topologically identical subgraphs and 2) a measurement of similaritybetween proteins by using Gene Ontology [1]. For validation of our method, we implemented a software tool and compared its performancewiththat of PathBLAST [2] onthe search of MAPK signal transduction cascade[3]. The result showed that our software tool detects correct answers with low false-positive rate. This tool wi11 provide better performance when combined with computational method of predicting proteinfunctions. | |||||
書誌情報 | 発行日 2005 | |||||
フォーマット | ||||||
内容記述タイプ | Other | |||||
内容記述 | application/pdf | |||||
日本十進分類法 | ||||||
主題 | 439.4 | |||||
主題Scheme | NDC | |||||
学位 | ||||||
値 | master | |||||
研究科・専攻 | ||||||
新領域創成科学研究科情報生命科学専攻 | ||||||
学位授与年月日 | ||||||
学位授与年月日 | 2005-03 |