ログイン
言語:

WEKO3

  • トップ
  • コミュニティ
  • ランキング
AND
To
lat lon distance
To

Field does not validate



インデックスリンク

インデックスツリー

メールアドレスを入力してください。

WEKO

One fine body…

WEKO

One fine body…

アイテム

{"_buckets": {"deposit": "45bb3bb4-9086-4358-b9b7-0339c561b4f4"}, "_deposit": {"id": "175", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "175"}, "status": "published"}, "_oai": {"id": "oai:repository.dl.itc.u-tokyo.ac.jp:00000175"}, "item_2_biblio_info_7": {"attribute_name": "\u66f8\u8a8c\u60c5\u5831", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2004", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "11", "bibliographicPageEnd": "1124", "bibliographicPageStart": "1121", "bibliographicVolumeNumber": "21", "bibliographic_titles": [{"bibliographic_title": "Zoological science"}]}]}, "item_2_description_13": {"attribute_name": "\u30d5\u30a9\u30fc\u30de\u30c3\u30c8", "attribute_value_mlt": [{"subitem_description": "application/pdf", "subitem_description_type": "Other"}]}, "item_2_description_5": {"attribute_name": "\u6284\u9332", "attribute_value_mlt": [{"subitem_description": "Crustacean hyperglycemic hormone (CHH) and molt-inhibiting hormone (MIH) have similar amino acid sequences and therefore comprise a peptide family referred to as the CHH family. All MIHs unexceptionally have an additional glycine residue at position 12, which is lacking in all CHHs. In order to understand the relevance of the absence of the glycine residue for hyperglycemic activity, a mutant CHH having a glycine residue insertion was prepared, and its hyperglycemic activity was assessed. This mutant CHH had the same disulfide bond arrangement as the recombinant CHH produced in Escherichia coli cells, and exhibited a similar circular dichroism spectrum to the recombinant CHH, indicating that the two CHHs possessed similar conformations. The mutant CHH showed a hyperglycemic effect weaker than the recombinant CHH by about one order of magnitude. These results suggest that the insertion of a glycine residue is one of the indices for structural and functional divergence of the CHH family peptides.", "subitem_description_type": "Abstract"}]}, "item_2_full_name_3": {"attribute_name": "\u8457\u8005\u5225\u540d", "attribute_value_mlt": [{"nameIdentifiers": [{"nameIdentifier": "105907", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "\u9577\u6fa4, \u5bdb\u9053"}]}]}, "item_2_publisher_20": {"attribute_name": "\u51fa\u7248\u8005", "attribute_value_mlt": [{"subitem_publisher": "Zoological Society of Japan"}]}, "item_2_relation_11": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type_id": {"subitem_relation_type_id_text": "info:doi/10.2108/zsj.21.1121", "subitem_relation_type_select": "DOI"}}]}, "item_2_source_id_10": {"attribute_name": "\u66f8\u8a8c\u30ec\u30b3\u30fc\u30c9ID", "attribute_value_mlt": [{"subitem_source_identifier": "AA10545874", "subitem_source_identifier_type": "NCID"}]}, "item_2_source_id_8": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "02890003", "subitem_source_identifier_type": "ISSN"}]}, "item_2_subject_15": {"attribute_name": "\u65e5\u672c\u5341\u9032\u5206\u985e\u6cd5", "attribute_value_mlt": [{"subitem_subject": "480", "subitem_subject_scheme": "NDC"}]}, "item_2_text_21": {"attribute_name": "\u51fa\u7248\u8005\u5225\u540d", "attribute_value_mlt": [{"subitem_text_value": "\u65e5\u672c\u52d5\u7269\u5b66\u4f1a"}]}, "item_2_text_34": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"subitem_text_value": "Journal Article"}]}, "item_2_text_4": {"attribute_name": "\u8457\u8005\u6240\u5c5e", "attribute_value_mlt": [{"subitem_text_value": "Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo"}, {"subitem_text_value": "Institute for Protein Research, Osaka University"}]}, "item_creator": {"attribute_name": "\u8457\u8005", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Katayama, Hidekazu"}], "nameIdentifiers": [{"nameIdentifier": "105905", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Nagasawa, Hiromichi"}], "nameIdentifiers": [{"nameIdentifier": "105906", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "\u30d5\u30a1\u30a4\u30eb\u60c5\u5831", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2017-06-26"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "ZS21_1121.pdf", "filesize": [{"value": "125.1 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 125100.0, "url": {"label": "ZS21_1121.pdf", "url": "https://repository.dl.itc.u-tokyo.ac.jp/record/175/files/ZS21_1121.pdf"}, "version_id": "0f36eb79-0d3b-4edc-bf42-877532a44a60"}]}, "item_keyword": {"attribute_name": "\u30ad\u30fc\u30ef\u30fc\u30c9", "attribute_value_mlt": [{"subitem_subject": "crustacean hyperglycemic hormone", "subitem_subject_scheme": "Other"}, {"subitem_subject": "kuruma prawn", "subitem_subject_scheme": "Other"}, {"subitem_subject": "mutational analysis", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "\u8a00\u8a9e", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Effect of a glycine residue insertion into crustacean hyperglycemic hormone on hormonal activity", "item_titles": {"attribute_name": "\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_title": "Effect of a glycine residue insertion into crustacean hyperglycemic hormone on hormonal activity"}]}, "item_type_id": "2", "owner": "1", "path": ["9/10/11", "27/38/39"], "permalink_uri": "http://hdl.handle.net/2261/8076", "pubdate": {"attribute_name": "\u516c\u958b\u65e5", "attribute_value": "2007-12-14"}, "publish_date": "2007-12-14", "publish_status": "0", "recid": "175", "relation": {}, "relation_version_is_last": true, "title": ["Effect of a glycine residue insertion into crustacean hyperglycemic hormone on hormonal activity"], "weko_shared_id": null}
  1. 116 農学生命科学研究科・農学部
  2. 04 応用生命化学専攻
  3. 1160410 学術雑誌論文
  1. 0 資料タイプ別
  2. 10 学術雑誌論文
  3. 014 自然科学

Effect of a glycine residue insertion into crustacean hyperglycemic hormone on hormonal activity

http://hdl.handle.net/2261/8076
e334ae9d-bc1f-4730-bfd2-0563adf514b0
名前 / ファイル ライセンス アクション
ZS21_1121.pdf ZS21_1121.pdf (125.1 kB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2007-12-14
タイトル
タイトル Effect of a glycine residue insertion into crustacean hyperglycemic hormone on hormonal activity
言語
言語 eng
キーワード
主題 crustacean hyperglycemic hormone
主題Scheme Other
キーワード
主題 kuruma prawn
主題Scheme Other
キーワード
主題 mutational analysis
主題Scheme Other
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ journal article
著者 Katayama, Hidekazu

× Katayama, Hidekazu

WEKO 105905

Katayama, Hidekazu

Search repository
Nagasawa, Hiromichi

× Nagasawa, Hiromichi

WEKO 105906

Nagasawa, Hiromichi

Search repository
著者別名
識別子
識別子 105907
識別子Scheme WEKO
姓名
姓名 長澤, 寛道
著者所属
著者所属 Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo
著者所属
著者所属 Institute for Protein Research, Osaka University
抄録
内容記述タイプ Abstract
内容記述 Crustacean hyperglycemic hormone (CHH) and molt-inhibiting hormone (MIH) have similar amino acid sequences and therefore comprise a peptide family referred to as the CHH family. All MIHs unexceptionally have an additional glycine residue at position 12, which is lacking in all CHHs. In order to understand the relevance of the absence of the glycine residue for hyperglycemic activity, a mutant CHH having a glycine residue insertion was prepared, and its hyperglycemic activity was assessed. This mutant CHH had the same disulfide bond arrangement as the recombinant CHH produced in Escherichia coli cells, and exhibited a similar circular dichroism spectrum to the recombinant CHH, indicating that the two CHHs possessed similar conformations. The mutant CHH showed a hyperglycemic effect weaker than the recombinant CHH by about one order of magnitude. These results suggest that the insertion of a glycine residue is one of the indices for structural and functional divergence of the CHH family peptides.
書誌情報 Zoological science

巻 21, 号 11, p. 1121-1124, 発行日 2004
ISSN
収録物識別子タイプ ISSN
収録物識別子 02890003
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AA10545874
DOI
関連識別子
識別子タイプ DOI
関連識別子 info:doi/10.2108/zsj.21.1121
フォーマット
内容記述タイプ Other
内容記述 application/pdf
日本十進分類法
主題 480
主題Scheme NDC
出版者
出版者 Zoological Society of Japan
出版者別名
日本動物学会
戻る
0
views
See details
Views

Versions

Ver.1 2021-03-02 00:45:07.075394
Show All versions

Share

Mendeley CiteULike Twitter Facebook Print Addthis

Cite as

Export

OAI-PMH
  • OAI-PMH JPCOAR
  • OAI-PMH DublinCore
  • OAI-PMH DDI
Other Formats
  • JSON
  • BIBTEX

Confirm


Powered by CERN Data Centre & Invenio


Powered by CERN Data Centre & Invenio