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Functional and anatomical organization of forward projection from area TE to perirhinal neurons representing visual long-term memory in monkeys
https://doi.org/10.15083/00002085
https://doi.org/10.15083/00002085b9d53681-0180-4c96-b949-c57d74d6f4fd
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
K-215724.pdf (4.5 MB)
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| Item type | 学位論文 / Thesis or Dissertation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2012-02-28 | |||||
| タイトル | ||||||
| タイトル | Functional and anatomical organization of forward projection from area TE to perirhinal neurons representing visual long-term memory in monkeys | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源 | http://purl.org/coar/resource_type/c_46ec | |||||
| タイプ | thesis | |||||
| ID登録 | ||||||
| ID登録 | 10.15083/00002085 | |||||
| ID登録タイプ | JaLC | |||||
| その他のタイトル | ||||||
| その他のタイトル | 大脳側頭葉長期記憶ニューロンへの神経投射の放散度 : 生理学的解剖学的手法による定量的解析 | |||||
| 著者 |
Yoshida, Masatoshi
× Yoshida, Masatoshi |
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| 著者別名 | ||||||
| 識別子Scheme | WEKO | |||||
| 識別子 | 6085 | |||||
| 姓名 | 吉田, 正俊 | |||||
| Abstract | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | A number of studies have shown that the perirhinal (PRh) cortex, which is part of the medial temporal lobe memory system, plays an important role in declarative long-term memory. The PRh cortex contains neurons that represent visual long-term memory. The aim of the present study is to characterize the anatomical organization of forward projections that mediate information flow from visual area TE to memory neurons in the PRh cortex. In monkeys performing a visual pair-association memory task, I conducted an extensive mapping of neuronal responses in anteroventral area TE (TEav) and area 36 (A36) of the PRh cortex. Then, three retrograde tracers were separately injected into A36 and the distribution of retrograde labels in TEav was analyzed. I focused on the degree of divergent projections from TEav to memory neurons in A36, because the highly divergent nature of these forward fiber projections has been implicated in memory function. I found that the degree of divergent projection to memory neurons in A36 was smaller from the TEav neurons selective to learned pictures than from the nonselective TEav neurons. This result demonstrates that the anatomical difference (the divergence) correlates with the physiological difference (selectivity of TEav neurons to the learned pictures). Because the physiological difference is attributed to whether or not the projections are involved in information transmission required for memory neurons in A36, it can be speculated that the reduced divergent projection resulted from acquisition of visual long-term memory, possibly through retraction of the projecting axon collaterals. | |||||
| 書誌情報 | 発行日 2003-06-18 | |||||
| 日本十進分類法 | ||||||
| 主題Scheme | NDC | |||||
| 主題 | 491 | |||||
| 学位名 | ||||||
| 学位名 | 博士(医学) | |||||
| 学位 | ||||||
| 値 | doctoral | |||||
| 学位分野 | ||||||
| Medical Science(医学) | ||||||
| 学位授与機関 | ||||||
| 学位授与機関名 | University of Tokyo (東京大学) | |||||
| 研究科・専攻 | ||||||
| Graduate School of Medicine (医学系研究科) | ||||||
| 学位授与年月日 | ||||||
| 学位授与年月日 | 2003-06-18 | |||||
| 学位授与番号 | ||||||
| 学位授与番号 | 乙第15724号 | |||||
| 学位記番号 | ||||||
| 第15724号 | ||||||
