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子宮脱落膜の分化不全による新しい不妊症メカニズムの解明
https://doi.org/10.15083/00005573
a931ace2-c781-45b4-baa1-00eca7628671
名前 / ファイル | ライセンス | アクション | |
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Item type | 学位論文 / Thesis or Dissertation(1) | |||||
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公開日 | 2014-02-24 | |||||
タイトル | ||||||
タイトル | 子宮脱落膜の分化不全による新しい不妊症メカニズムの解明 | |||||
言語 | ||||||
言語 | jpn | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_46ec | |||||
タイプ | thesis | |||||
ID登録 | ||||||
ID登録 | 10.15083/00005573 | |||||
ID登録タイプ | JaLC | |||||
その他のタイトル | ||||||
その他のタイトル | A novel mechanism for infertility caused by impaired development of uterine decidualization | |||||
著者 |
森, 真弓
× 森, 真弓 |
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著者別名 | ||||||
識別子 | ||||||
識別子 | 11622 | |||||
識別子Scheme | WEKO | |||||
姓名 | ||||||
姓名 | もり, まゆみ | |||||
著者所属 | ||||||
著者所属 | 東京大学大学院医学系研究科分子細胞生物学専攻 | |||||
Abstract | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | 母体内で着床後の胚が正常に発生・成長するためには、子宮の機能が極めて重要である。特に、胎盤が形成される前に胚に栄養を送る脱落膜組織は重要であるにも関わらず、未だその機能における分子メカニズムがわかっていない。私は、death effector domain-containing protein (Dedd)欠損マウスが呈するメス不妊症の原因が脱落膜分化不全にあることを明らかにし、その分子メカニズムを解明するとともに、女性不妊症において脱落膜の機能分化が原因かつ治療のターゲットの一つになり得る可能性を示した。 | |||||
書誌情報 | 発行日 2012-03-22 | |||||
日本十進分類法 | ||||||
主題 | 490 | |||||
主題Scheme | NDC | |||||
学位名 | ||||||
学位名 | 博士(医学) | |||||
学位 | ||||||
値 | doctoral | |||||
学位分野 | ||||||
Medical Science(医学) | ||||||
学位授与機関 | ||||||
学位授与機関名 | ||||||
学位授与機関名 | University of Tokyo (東京大学) | |||||
研究科・専攻 | ||||||
Department of Molecular Cell Biology, Graduate School of Medicine (医学系研究科分子細胞生物学専攻) | ||||||
学位授与年月日 | ||||||
学位授与年月日 | 2012-03-22 | |||||
学位授与番号 | ||||||
学位授与番号 | 甲第28137号 | |||||
学位記番号 | ||||||
博医第3796号 |