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Adherence to antiretroviral therapy (ART), self-stigma and depression among people living with HIV (PLWH) in rural Zambia
https://doi.org/10.15083/00005584
https://doi.org/10.15083/000055847bd88fe6-4e74-490c-a118-47c967c88ca2
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
h23_sasaki.pdf (1.9 MB)
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| Item type | 学位論文 / Thesis or Dissertation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2014-02-24 | |||||
| タイトル | ||||||
| タイトル | Adherence to antiretroviral therapy (ART), self-stigma and depression among people living with HIV (PLWH) in rural Zambia | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | HIV | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Antiretroviral therapy (ART) | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Adherence | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Self-stigma | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Depression | |||||
| 資源タイプ | ||||||
| 資源 | http://purl.org/coar/resource_type/c_46ec | |||||
| タイプ | thesis | |||||
| ID登録 | ||||||
| ID登録 | 10.15083/00005584 | |||||
| ID登録タイプ | JaLC | |||||
| その他のタイトル | ||||||
| その他のタイトル | ザンビア共和国農村部におけるHIV陽性者の抗レトロウィルス療法に対する服薬遵守及びセルフスティグマと抑うつ症状について | |||||
| 著者 |
Sasaki, Yuri
× Sasaki, Yuri |
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| 著者別名 | ||||||
| 識別子Scheme | WEKO | |||||
| 識別子 | 11644 | |||||
| 姓名 | 佐々木, 由理 | |||||
| 著者所属 | ||||||
| 著者所属 | 東京大学大学院医学系研究科国際保健学専攻 | |||||
| Abstract | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Introduction: Sustaining high levels of adherence to antiretroviral therapy (ART) is a challenge in Zambia. This study aimed to identify the factors associated with ART adherence and to examine the relationship among ART adherence, self-stigma and depressive symptoms at the early months of treatment in rural Zambia.// Method: This is a field based observational longitudinal study in Mumbwa. Treatment naïve clients aged over 15 years, who initiated ART during September-November 2010, were enrolled. Clients were interviewed at the initiation of ART and at six weeks later. Clients'self-report was used for measuring ART adherence.// Result: Of 157 clients, 59.9% were fully adherent. In multivariable analysis, full adherence was associated with being female [Adjusted odds ratio (AOR), 6.4; 95% Confidence interval (CI), 1.7-23.5], experience of food insufficiency in the previous 30 days (AOR, 5.7; 95% CI, 1.6-21.2), spouse undergoing ART (AOR, 5.4; 95% CI, 1.4-19.9), self-stigma at the initiation of ART (AOR, 0.1; 95% CI, 0.02-0.6), being more depressed (AOR, 1.1; 95% CI, 1.0-1.3) and having less self-stigma (AOR, 0.6; 95% CI, 0.5-0.9) after six weeks compared with at the initiation of ART.// Conclusion: ART adherence continues to be a significant behavioral challenge in rural Zambia. Sex, food issues, spouse's ART use and mental health issues were associated with ART adherence. These are likely the issues that ART services will need to focus on in the future beyond current efforts such as increasing accessibility by expanding mobile ART services in rural Zambia. | |||||
| 書誌情報 | 発行日 2012-03-22 | |||||
| 日本十進分類法 | ||||||
| 主題Scheme | NDC | |||||
| 主題 | 490 | |||||
| 学位名 | ||||||
| 学位名 | 博士(保健学) | |||||
| 学位 | ||||||
| 値 | doctoral | |||||
| 学位分野 | ||||||
| Health Science(保健学) | ||||||
| 学位授与機関 | ||||||
| 学位授与機関名 | University of Tokyo (東京大学) | |||||
| 研究科・専攻 | ||||||
| Department of International Health, Graduate School of Medicine (医学系研究科国際保健学専攻) | ||||||
| 学位授与年月日 | ||||||
| 学位授与年月日 | 2012-03-22 | |||||
| 学位授与番号 | ||||||
| 学位授与番号 | 甲第28311号 | |||||
| 学位記番号 | ||||||
| 博医第3970号 | ||||||
