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High-throughput formation of lipid bilayer membrane arrays with an asymmetric lipid composition
http://hdl.handle.net/2261/56336
http://hdl.handle.net/2261/56336f61ba5c7-e3cb-4eae-aa5c-4f37e265c68f
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
srep07076.pdf (923.9 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
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| 公開日 | 2015-03-26 | |||||
| タイトル | ||||||
| タイトル | High-throughput formation of lipid bilayer membrane arrays with an asymmetric lipid composition | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源 | http://purl.org/coar/resource_type/c_6501 | |||||
| タイプ | journal article | |||||
| 著者 |
Watanabe, Rikiya
× Watanabe, Rikiya× Soga, Naoki× Yamanaka, Tomoko× Noji, Hiroyuki |
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| 著者所属 | ||||||
| 著者所属 | Department of Applied Chemistry, Graduate School of Engineering, The University of Tokyo | |||||
| 著者所属 | ||||||
| 著者所属 | PRESTO, JST | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | We present a micro-device in which more than 10,000 asymmetric lipid bilayer membranes are formed at a time on micro-chamber arrays. The arrayed asymmetric lipid bilayers, where lipid compositions are different between the inner and outer leaflets, are formed with high efficiency of over 97% by injecting several types of liquids into a micro-device that has hydrophilic-in-hydrophobic surfaces. The lipid compositional asymmetry is an intrinsic property of bio-membranes, and therefore, this micro-device extends the versatility of artificial lipid-bilayer systems, which were previously limited to symmetric bilayer formation, and could contribute to the understanding of the role of lipid compositional asymmetry in cell physiology and also to further analytical and pharmacological applications. | |||||
| 内容記述 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | UTokyo Research掲載「脂質組成の非対称性をもつ人工生体膜の新しい量産技術」 URI: http://www.u-tokyo.ac.jp/ja/utokyo-research/research-news/novel-high-throughput-micro-device-to-form-asymmetric-bio-membranes/ | |||||
| 内容記述 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | UTokyo Research "Novel high-throughput micro-device to form asymmetric bio-membranes" URI: http://www.u-tokyo.ac.jp/en/utokyo-research/research-news/novel-high-throughput-micro-device-to-form-asymmetric-bio-membranes/ | |||||
| 書誌情報 |
Scientific Repoorts 巻 4, p. 7076, 発行日 2014-11-17 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 2045-2322 | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | info:doi/10.1038/srep07076 | |||||
| 権利 | ||||||
| 権利情報 | This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder in order to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/4.0/ | |||||
| 著者版フラグ | ||||||
| 値 | publisher | |||||
| 出版者 | ||||||
| 出版者 | Nature Publishing Group | |||||
| 関係URI | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | http://www.u-tokyo.ac.jp/ja/utokyo-research/research-news/novel-high-throughput-micro-device-to-form-asymmetric-bio-membranes/ | |||||
| 関係URI | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | http://www.u-tokyo.ac.jp/en/utokyo-research/research-news/novel-high-throughput-micro-device-to-form-asymmetric-bio-membranes/ | |||||
| 関係URI | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | http://www.nature.com/srep/2014/141117/srep07076/full/srep07076.html | |||||
