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組織工学材料における血管新生の生体内連続観察
https://doi.org/10.15083/00004071
08e37b38-4b1f-428b-b7f1-8cac3c3ce2d4
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Item type | 学位論文 / Thesis or Dissertation(1) | |||||
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公開日 | 2012-11-08 | |||||
タイトル | ||||||
タイトル | 組織工学材料における血管新生の生体内連続観察 | |||||
言語 | ||||||
言語 | jpn | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_46ec | |||||
タイプ | thesis | |||||
ID登録 | ||||||
ID登録 | 10.15083/00004071 | |||||
ID登録タイプ | JaLC | |||||
その他のタイトル | ||||||
その他のタイトル | Real-time observation of angiogenesis for tissue engineering | |||||
著者 |
井上, 雄介
× 井上, 雄介 |
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著者別名 | ||||||
識別子 | ||||||
識別子 | 9404 | |||||
識別子Scheme | WEKO | |||||
姓名 | ||||||
姓名 | いのうえ, ゆうすけ | |||||
著者所属 | ||||||
著者所属 | 東京大学大学院医学系研究科生体物理医学専攻 | |||||
Abstract | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | 組織工学材料としてのScaffoldに新生する血管を長期間安定に観察するために、3種類の血管新生観察装置を開発した。高解像度CMOS受像素子とオートフォーカス機能を備えることにより画質の問題を解決した。開発した血管新生観察装置を用いることで、麻酔や沈静薬剤を必要とせず、かつ厳しい拘束なしに長期間安定して、Scaffoldにおける血管新生を連続観察できることを実証した。細胞播種がScaffoldにおける血管新生に与える影響について検討し、細胞を播種した方が細胞を播種しない場合よりもScaffoldにおける血管新生の速度が早いことを明らかにした。本研究で開発した血管新生観察装置は、様々な研究に応用可能であり、その有用性が期待できると考えられる。 | |||||
書誌情報 | 発行日 2011-03-24 | |||||
日本十進分類法 | ||||||
主題 | 490 | |||||
主題Scheme | NDC | |||||
学位名 | ||||||
学位名 | 博士(医学) | |||||
学位 | ||||||
値 | doctoral | |||||
学位分野 | ||||||
Medical Science(医学) | ||||||
学位授与機関 | ||||||
学位授与機関名 | ||||||
学位授与機関名 | University of Tokyo (東京大学) | |||||
研究科・専攻 | ||||||
Department of Radiology and Biomedical Engineering, Graduate School of Medicine (医学系研究科生体物理医学専攻) | ||||||
学位授与年月日 | ||||||
学位授与年月日 | 2011-03-24 | |||||
学位授与番号 | ||||||
学位授与番号 | 甲第27002号 | |||||
学位記番号 | ||||||
博医第3612号 |